Study Links Ibuprofen to Male Infertility

  • Study Links Ibuprofen to Male Infertility

Study Links Ibuprofen to Male Infertility

However, despite the change in LH levels, the men's testosterone levels didn't change.

However, Kristensen emphasises that despite the results of the study, men should not stop taking the drug.

Male fertility is dropping around the world and the researchers wanted to see if ibuprofen might be contributing to this.

Researchers looked at 31 male participants and found that taking ibuprofen reduced production of testosterone by almost a quarter in the space of around six weeks. Some took 1,200 milligrams of ibuprofen - commonly known as Advil or Motrin, among others - every day in two 600 mg doses over a six-week period, while others received a placebo.

While this effect wasn't permanent, the researchers warned that prolonged use of ibuprofen by men could lead to low testosterone production - which might end up harming their fertility.

"We normally see this condition in elderly men, so it raises an alarm", study co-author Bernard Jégou of the French National Institute of Health and Medical Research, told The Guardian.

'Several studies have shown mild analgesics exposure during foetal life is associated with anti-androgenic effects and congenital malformations. But researchers are concerned about long-term use among athletes. "This study should give pause for thought to sportsmen using them routinely for exercise-induced aches and pains".

The human brain compensates for testosterone deficiency by producing luteinizing hormone (LH), which sends a signal to the testicles to produce more testosterone.

A study of nearly 1,000 men tracked for seven years found that twice as many with hypogonadism died as did those with normal testosterone levels.

"However, this is now speculative".

Ibuprofen has also been linked to increased risk of heart attacks or stroke in those who take it long term.

To avoid these side-effects, doctors caution against taking Ibuprofen for more longer than ten days in a row, per the FDA's warning.

The study was first tested on women, according to CNN.

Even though this was a small study and further research is needed, the findings are important because ibuprofen is one of the most widely-used medications, Erma Drobnis, an associate professional practice professor of reproductive medicine and fertility at the University of Missouri, Columbia, told CNN.